Effect of Energy Restriction on Malondialdehyde Levels in Rats

Elevated malondialdehyde (MDA) levels indicate the occurrence of cell membrane oxidation. Calorie restriction is known to extend life expectancy. This study aims investigate effect calorie on MDA in young and old rats. An experimental approach was employed using Rattus norvegicus Wistar strain as animals, with a pre-post-test control group design. A total 28 white rats were included this divided into four groups. The groups, Group B, received standard feed unrestricted access distilled water, while treatment C D, fed 40% reduction intake water. Data analysis performed SPSS 21.0 (SPSS, Inc., Chicago, IL) 0.05 significance level. results showed difference level changes between B (control group) D (treatment (p<0.05). concludes that are higher elderly compared rats, can reduce levels.